Brain secretory peptides of the silkmoth Bombyx mori: prothoracicotropic hormone and bombyxin.
نویسندگان
چکیده
Evolutionary Aspects of Neuropeptides and their Genes Structure and evolution of insulin and insulin-like growth factors in chordates p. 15 Relationships among the FMRFamide-like peptides p. 25 Molecular evolution of neurohypophysial hormone precursors p. 39 A vasopressin-related peptide in the mollusc Lymnaea stagnalis: Peptide structure, prohormone organization, evolutionary and functional aspects of Lymnaea conopressin p. 47
منابع مشابه
Molecular characterization of the brain secretory peptides, prothoracicotropic hormone (PTTH) and bombyxin, of the silkmoth Bombyx mori
Molecular characterization of the brain secretory peptides, PTTH and bombyxin, of Bombyx mori is reviewed. PTTH is a 30-kDa homodimeric glycoprotein, the monomer of which consists of 109 amino acids. Two monomers are held together by a disulfide bond. cDNA and gene coding for PTTH were cloned and the precursor protein for PTTH monomer was deduced. A novel 5-kD brain secretory peptide named bomb...
متن کاملcDNA structure and expression of bombyxin, an insulin-like brain secretory peptide of the silkmoth Bombyx mori.
Bombyxin, previously referred to as 4K-prothoracicotropic hormone, is a brain peptide of the silkmoth Bombyx mori, the amino acid sequence of which shows considerable homology with vertebrate insulin family peptides. Two independent clones have been isolated from a Bombyx larval brain cDNA library by using a synthetic oligonucleotide probe, one with the complete coding region for preprobombyxin...
متن کاملInsulin-like and IGF-like peptides in the silkmoth Bombyx mori: discovery, structure, secretion, and function
A quarter of a century has passed since bombyxin, the first insulin-like peptide identified in insects, was discovered in the silkmoth Bombyx mori. During these years, bombyxin has been studied for its structure, genes, distribution, hemolymph titers, secretion control, as well as physiological functions, thereby stimulating a wide range of studies on insulin-like peptides in other insects. Mor...
متن کاملIdentification of novel bombyxin genes from the genome of the silkmoth Bombyx mori and analysis of their expression.
Insulin family peptide members play key roles in regulating growth, metabolism, and reproduction. Bombyxin is an insulin-related peptide of the silkmoth Bombyx mori. We analyzed the full genome of B. mori and identified five novel bombyxin families, V to Z. We characterized the genomic organization and chromosomal location of the novel bombyxin family genes. In contrast to previously identified...
متن کاملPTTH--a potential growth activator in silkworm, Bombyx mori L. for enhancing silk production.
In silkworm, prothoracicotropic hormone (PTTH), directly or indirectly controls silk production and spinning activity along with juvenile hormone (JH). An effort was made to exploit the potential of PTTH by indirectly activating silk gland for increasing silk productivity using short chain synthetic analogues of PTTH. The analogy in action was also established using PTTH extracted from the silk...
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ورودعنوان ژورنال:
- Progress in brain research
دوره 92 شماره
صفحات -
تاریخ انتشار 1992